Reactivity of Langerhans cells with hybridoma antibody.
نویسندگان
چکیده
منابع مشابه
Hybridoma Monoclonal Antibody: Distribution on Benign and Malignant Lymphoid Cells
A hybridoma-derived monoclonal antibody. produced by immunization with the Burkitt’s tumor-derived B-Iymphoblastoid cell line. B35M. was previously shown to detect a 68.000 dalton surface membrane protein. B12. on the surface of peripheral blood B cells. which is absent from thymocytes. T cells. and granulocytes. In this study. we investigated the expression and distribution of B12 on benign an...
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Background Traditionally antibody producing cells like hybridoma cells sank into oblivion since other suspension cell lines have captured the biopharmaceutical production market. However, they are still of particular interest in academic and industrial diagnostic research. Hence, fast and sufficient antibody production is needed as proof of concept, for toxicology and in vivo studies. Although,...
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Background: Langerhans cells are important in the pathogenesis of leprosy. A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1981
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.78.4.2541